Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594

The best Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594, quick delivery, high quality.

Product price

489 EUR

Product size

100 microliters

Product catalog no.

GENTObsm-2346M-A594

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Background information

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

Advisory

Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.

 

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Synonyms

Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.

 

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Storage

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

 

Alternative name 1

P53(wt-p53) (D2F7) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated

Alternative name 2

P53(wt-p53) (D2F7) Monoclonal anti-, ALEXA FLUOR 594 Conjugated

 

Antigen Source

KLH conjugated synthetic peptide derived from human P53(wt-p53)

Cross Reactive species

Human (Homo sapiens), Rat (Rattus norvegicus)

 

Cross Reactive Species details

No significant cross reactivity is observed

Specificity

Highly specific antibody against P53wt-p53

 

Properties

For facs or microscopy Alexa 1 conjugate.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

 

Type

Conjugated Primary Antibody

Purification method

Purified by Protein G.

 

Clonality

Monoclonal Antibodies

Host organism

Mouse (Mus musculus)

 

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Conjugated

Alexa conjugate 1

 

Conjugated with

ALEXA FLUOR 594

Modification

Not modified

 

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

 

Target Protein/Peptide

P53wt-p53

Applications

IF(IHC-P)

 

Clone

D2F7

Gene ID

7157