Quick contact, quick delivery, greatests SL-01, p53/mdm2 inhibitor prices.
128 EUR
50 mg
SIH-343-50MG
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Chemical structure of SL-01 (SIH-343), a p53/mdm2 inhibitor. CAS #: 26049-94-5. Molecular Formula: C18H18ClNO3. Molecular Weight: 331.8 g/mol. Chemical structure of SL-01, a p53/mdm2 inhibitor (SIH-343). CAS # 26049-94-5. Molecular Formula: C18H18ClNO3.
Classification: Caution – Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate; N-Benzyloxycarbonyl-Lphenylalaninylchloromethyl ketone; ZPCK
Inhibits the p53-MDM2 interaction (20 µM). Has also been shown to inhibit bovine chymotrypsin A-y.
Cancer, Apoptosis, Cancer Growth Inhibitors, p53/mdm2 Inhibitors
Soluble in 50 mg/ml DMSO oir 15 mg/ml warm Ethanol
1. Li J., et al. (2011) J Biol Screening 16: 450.
>98% (TLC); NMR (Conforms)
p53/mdm2 inhibitor
Refer to PubMed
Shipped Ambient
Small Molecules
Non-hazardous
To be tested
To be tested
17-Aug-2012
331,8 g/mol
White Solid
C18H18ClNO3
26049-94-5
Inhibitor
Synthetic
In Stock
-20ºC
Canada
99625
0.25
0.05