Anti-P53(Thr18) (Polyclonal), ALEXA Fluor 594

The best quality, top Anti-P53(Thr18) (Polyclonal), ALEXA Fluor 594 prices, fast delivery.

Product price

516 EUR

Product size

100 microliters

Product catalog no.

GENTObs-3710R-A594

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Background information

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

 

Synonyms

p53 Thr18; P53 phospho S18; P53 phospho Ser18; p-P53 Ser18; p-P53 S18; Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

 

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

 

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Antigen Source

KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Thr18

 

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Specificity

This antibody reacts specifically with P53(Thr18)

 

Properties

For facs or microscopy Alexa 1 conjugate.

Also known as

P53(Thr18) Polyclonal Antibody

 

Host organism

Rabbit (Oryctolagus cuniculus)

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

 

Type

Conjugated Primary Antibody

Group

Polyclonals and antibodies

 

Other name

Anti-P53(Thr18) Polyclonal

Purification method

Purified by Protein A.

 

Clone

Polyclonal Antibodies

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

 

Clonality

Polyclonal Antibody

Conjugated

Alexa conjugate 1

 

Conjugated with

ALEXA FLUOR® 594

Modification

Phosphorylation

 

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

 

Target Protein/Peptide

P53 Thr18

Applications

IF(IHC-P)

 

Modification site

Thr18

Gene ID

7157

 

Subcellular locations

N/A

Swiss Prot

N/A