p53 DINP1 Antibody

The best quality, top p53 DINP1 Antibody prices, fast delivery.

Product price

263 EUR

Product size

0.1ml

Product catalog no.

bs-6146R

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Background of the target antigen

Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p53 DINP1

 

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonym names

Tumor protein p53-inducible nuclear protein 1; TP53INP1; P53DINP1; SIP

 

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Specificity

This is a highly specific antibody against p53 DINP1.

 

Purification method

This antibody was purified via Protein A.

Long name

p53 DINP1 Primary Polyclonal Antibody

 

Tested Applications

WB, IHC-P, IF(IHC-P)

Clone number

Polyclonal antibody

 

Clonality

Polyclonal antibody

Modification site(s)

Unmodified antibody

 

Category

Primary Antibodies

Cross reactivity

Human, Mouse, Rat

 

Also known as

p53 DINP1 PAb

Conjugation

Unconjugated

 

Concentration

1ug per 1ul

Target Antigen

p53 DINP1

 

French translation

anticorps

Gene ID number

94241

 

Modification(s)

None