p53BP1 Antibody

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Product price

263 EUR

Product size

0.1ml

Product catalog no.

bs-2740R

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Background of the target antigen

p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Synonym names

53 BP1; FLJ41424; MGC138366; p202; p53 binding protein 1; p53 BP1; p53BP1; TP53 BP1; TP53BP1; Tumor protein 53 binding protein 1; Tumor protein p53 binding protein 1; Tumor suppressor p53 binding protein 1; TP53B_HUMAN; tumor protein 53-binding protein, 1.

 

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

 

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p53BP1

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

 

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Specificity

This is a highly specific antibody against p53BP1.

 

Purification method

This antibody was purified via Protein A.

Long name

p53BP1 Primary Polyclonal Antibody

 

Tested Applications

WB, IHC-P, IF(IHC-P)

Clone number

Polyclonal antibody

 

Clonality

Polyclonal antibody

Modification site(s)

Unmodified antibody

 

Category

Primary Antibodies

Cross reactivity

Human, Mouse

 

Conjugation

Unconjugated

Concentration

1ug per 1ul

 

Also known as

p53BP1 PAb

French translation

anticorps

 

Target Antigen

p53BP1

Gene ID number

7158

 

Modification(s)

None