OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)

The best quality, top OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA) prices, fast delivery.

Product price

227 EUR

Product size

0,01 mg

Product catalog no.

MBS2086492

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Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

Description

This 1 is suited for programmed cell-death studies.

 

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