ASPP2/p53BP2 Antibody, FITC Conjugated

The best ASPP2/p53BP2 Antibody, FITC Conjugated, quick delivery, high quality.

Product price

333 EUR

Product size

0.1ml

Product catalog no.

bs-1283R-FITC

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Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.

Antigen background

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

 

Synonyms

BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic peptide derived from human ASPP2

 

Specificity

This is a highly specific antibody against ASPP2/p53BP2.

Long name

ASPP2/p53BP2 Polyclonal Antibody, FITC Conjugated

 

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

 

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

 

Recommended dilutions

IF(IHC-P)(1:50-200)

Subcellular location

Cytoplasm, Nucleus

 

Additional conjugation

Anti-FITC Antibody

Crossreactivity

Human, Mouse, Rat

 

Immunogen_range

1090-1128/1128

Target Antigen

ASPP2/p53BP2

 

Concentration

1ug per 1ul

Excitation Emission

494nm/518nm

 

Clonality

Polyclonal

Modification

Unmodified

 

French translation

anticorps

Tested applications

IF(IHC-P)

 

Swiss Prot

Q13625

Modification site

None

 

Conjugation

FITC

Gene ID number

7159