The best P53 protein(wt-p53) Antibody, Cy5 Conjugated, quick delivery, high quality.
350 EUR
0.1ml
bs-0033R-Cy5
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
P53; BCC7; LFS1; TRP53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
This is a highly specific antibody against P53 proteinwt-p53.
P53 protein(wt-p53) Polyclonal Antibody, Cy5 Conjugated
KLH conjugated synthetic peptide derived from human P53
This antibody was purified via Protein A.
IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Rabbit (Oryctolagus cuniculus)
Conjugated Primary Antibodies
Polyclonal antibody
Cytoplasm, Nucleus
IF(IHC-P), IF(ICC)
Human, Mouse, Rat
P53 proteinwt-p53
625,650nm/670nm
1ug per 1ul
240-290/393
Polyclonal
Unmodified
anticorps
P04637
Cy5.5
None
7157
Cy5