ASPP2/p53BP2 Antibody, Cy3 Conjugated

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Product price

350 EUR

Product size

0.1ml

Product catalog no.

bs-1283R-Cy3

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Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-ASPP2/p53BP2 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.

Antigen background

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

 

Synonyms

BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic peptide derived from human ASPP2

 

Specificity

This is a highly specific antibody against ASPP2/p53BP2.

Long name

ASPP2/p53BP2 Polyclonal Antibody, Cy3 Conjugated

 

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

 

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

 

Excitation Emission

512,550nm/570,615nm

Recommended dilutions

IF(IHC-P)(1:50-200)

 

Additional conjugation

cy3 conjugation kit

Subcellular location

Cytoplasm, Nucleus

 

Crossreactivity

Human, Mouse, Rat

Immunogen_range

1090-1128/1128

 

Target Antigen

ASPP2/p53BP2

Concentration

1ug per 1ul

 

Clonality

Polyclonal

Modification

Unmodified

 

French translation

anticorps

Tested applications

IF(IHC-P)

 

Swiss Prot

Q13625

Modification site

None

 

Gene ID number

7159

Conjugation

Cy3