Anti-p53R2 (Polyclonal), ALEXA Fluor 594

The best Anti-p53R2 (Polyclonal), ALEXA Fluor 594, quick delivery, high quality.

Product price

489 EUR

Product size

100 microliters

Product catalog no.

GENTObs-4181R-A594

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Synonyms

DKFZp686M05248; MGC102856; MGC42116; MTDPS8A; MTDPS8B; p53 inducible ribonucleotide reductase small subunit 2 homolog; p53 inducible ribonucleotide reductase small subunit 2 like protein; p53 R2; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; Ribonucleoside diphosphate reductase M2 subunit B; Ribonucleoside-diphosphate reductase subunit M2 B; Ribonucleotide reductase M2 B TP53 inducible; Ribonucleotide reductase M2 B; Ribonucleotide reductase small subunit like 2 p53 inducible; RIR2B_HUMAN; RRM 2B; RRM2B; TP53 inducible ribonucleotide reductase M2 B; TP53-inducible ribonucleotide reductase M2 B.

Background information

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].

 

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

 

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

 

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

 

Antigen Source

KLH conjugated synthetic peptide derived from human p53R2/RRM2B

Modification

No modification has been applied to this antibody

 

Specificity

This antibody reacts specifically with p53R2

Properties

For facs or microscopy Alexa 1 conjugate.

 

Host organism

Rabbit (Oryctolagus cuniculus)

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

 

Type

Conjugated Primary Antibody

Group

Polyclonals and antibodies

 

Also known as

p53R2 Polyclonal Antibody

Purification method

Purified by Protein A.

 

Other name

Anti-p53R2 Polyclonal

Clone

Polyclonal Antibodies

 

Clonality

Polyclonal Antibody

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

 

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

 

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

 

Applications

IF(IHC-P)

Target Protein/Peptide

p53R2

 

Gene ID

50484

Modification site

None

 

Swiss Prot

N/A

Subcellular locations

N/A