anti- P53 antibody

The best anti- P53 antibody, quick delivery, high quality.

Product price

320 EUR

Product size

2X100μg

Product catalog no.

FNab06083

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Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.

 

Synonyms

Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, P53, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53

Properties

If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Image1

Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab06083(P53 antibody) at dilution of 1:100

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Image4

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06083(P53 antibody) at dilution of 1:1000

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100

 

Purity

≥95% as determined by SDS-PAGE

Purification

Immunogen affinity purified

 

Tested Application

ELISA, WB, IHC, IF

Immunogen

tumor protein p53

 

Specificity

Human, Rat

French translation

anticorps

 

Form

liquid

Calculated MW

53 kDa

 

Uniprot ID

P04637