P53(wt-p53) (D2F7) Monoclonal Antibody

The best quality, top P53(wt-p53) (D2F7) Monoclonal Antibody prices, fast delivery.

Product price

263 EUR

Product size

0.1ml

Product catalog no.

bsm-2346M

Fast and secure purchase process

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Background of the target antigen

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

 

Synonym names

Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P53(wt-p53)

 

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Specificity

This is a highly specific antibody against P53wt-p53.

 

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Also known as

P53(wt-p53) (D2F7) Monoclonal Antibody

 

Long name

P53(wt-p53) (D2F7) Monoclonal Antibody

Purification method

Purified by Protein G.

 

Tested Applications

WB, IHC-P, IF(IHC-P)

Modification site(s)

Unmodified antibody

 

Category

Primary Antibodies

Conjugation

Unconjugated

 

Concentration

1ug per 1ul

Clonality

Monoclonal

 

Cross reactivity

Human, Rat

French translation

anticorps

 

Target Antigen

P53wt-p53

Clone number

D2F7

 

Modification(s)

None

Gene ID number

7157