p53BP1 (Ser25 + Ser29) Antibody, FITC Conjugated

The best p53BP1 (Ser25 + Ser29) Antibody, FITC Conjugated, quick delivery, high quality.

Product price

350 EUR

Product size

0.1ml

Product catalog no.

bs-3020R-FITC

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Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Specificity

This is a highly specific antibody against p53BP1 Ser25 + Ser29. This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.

Antigen background

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

 

Source

KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

 

Synonyms

p202; 53BP1; Tumor suppressor p53-binding protein 1; p53-binding protein 1; p53BP1; TP53BP1

Long name

p53BP1 (Ser25 + Ser29) Antibody, FITC Conjugated

 

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

 

Category

Conjugated Primary Antibodies

Target Antigen

p53BP1 Ser25 + Ser29

 

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

 

Additional conjugation

Anti-FITC Antibody

Crossreactivity

Human, Mouse, Rat

 

Modification

Phosphorylation

Modification site

Ser25 + Ser29

 

Excitation Emission

494nm/518nm

Concentration

1ug per 1ul

 

Clonality

Polyclonal

French translation

anticorps

 

Tested applications

IF(IHC-P)

Immunogen_range

1-50/1972

 

Subcellular location

Nucleus

Swiss Prot

Q12888

 

Conjugation

FITC

Gene ID number

7158