ASPP2/p53BP2 Antibody, HRP Conjugated

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Product price

350 EUR

Product size

0.1ml

Product catalog no.

bs-1283R-HRP

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Antigen background

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.

 

Synonyms

BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic peptide derived from human ASPP2

 

Specificity

This is a highly specific antibody against ASPP2/p53BP2.

Long name

ASPP2/p53BP2 Polyclonal Antibody, HRP Conjugated

 

Purification method

This antibody was purified via Protein A.

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500)

 

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

 

Clone

Polyclonal antibody

Subcellular location

Cytoplasm, Nucleus

 

Crossreactivity

Human, Mouse, Rat

Immunogen_range

1090-1128/1128

 

Additional conjugation

HRP Conjugated

Target Antigen

ASPP2/p53BP2

 

Concentration

1ug per 1ul

Clonality

Polyclonal

 

Modification

Unmodified

French translation

anticorps

 

Tested applications

WB, IHC-P

Swiss Prot

Q13625

 

Modification site

None

Gene ID number

7159

 

Excitation Emission

N/A

Conjugation

HRP