P53(Ser46) Antibody, Biotin Conjugated

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Product price

350 EUR

Product size

0.1ml

Product catalog no.

bs-3707R-Biotin

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Antigen background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

 

Synonyms

p53Ser46; P53 phospho S46; P53 phospho Ser46; p-P53 Ser46; p-P53 S46; Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Source

KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser46

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

 

Specificity

This is a highly specific antibody against P53 Ser46.

Long name

P53(Ser46) Polyclonal Antibody, Biotin Conjugated

 

Purification method

This antibody was purified via Protein A.

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500)

 

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

 

Clone

Polyclonal antibody

Modification

Phosphorylation

 

Additional conjugation

Biotinylated

Concentration

1ug per 1ul

 

Clonality

Polyclonal

French translation

anticorps

 

Tested applications

WB, IHC-P

Target Antigen

P53 Ser46

 

Conjugation

Biotin

Crossreactivity

Human

 

Modification site

Ser46

Gene ID number

7157

 

Excitation Emission

N/A