p53BP1 (Ser25 + Ser29) Antibody, Biotin Conjugated

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Product price

350 EUR

Product size

0.1ml

Product catalog no.

bs-3020R-Biotin

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Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

 

Specificity

This is a highly specific antibody against p53BP1 Ser25 + Ser29. This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.

Antigen background

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

 

Source

KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

 

Synonyms

p202; 53BP1; Tumor suppressor p53-binding protein 1; p53-binding protein 1; p53BP1; TP53BP1

Long name

p53BP1 (Ser25 + Ser29) Antibody, Biotin Conjugated

 

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

 

Category

Conjugated Primary Antibodies

Target Antigen

p53BP1 Ser25 + Ser29

 

Clone

Polyclonal antibody

Crossreactivity

Human, Mouse, Rat

 

Recommended dilutions

IHC-P(1:100-500)

Modification

Phosphorylation

 

Modification site

Ser25 + Ser29

Additional conjugation

Biotinylated

 

Concentration

1ug per 1ul

Clonality

Polyclonal

 

French translation

anticorps

Immunogen_range

1-50/1972

 

Subcellular location

Nucleus

Swiss Prot

Q12888

 

Conjugation

Biotin

Tested applications

IHC-P

 

Gene ID number

7158

Excitation Emission

N/A