Quick contact, quick delivery, greatests p53 (FL-393) Antibody, ALEXA FLUOR 594 prices.
p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53.
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
p53 (FL-393) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
This is a highly specific antibody against p53 FL-393.
Anti-p53 FL-393 PAb ALEXA FLUOR 594
Rabbit (Oryctolagus cuniculus)
Full length human p53 protein
Conjugated Primary Antibodies
Alexa Fluor,ALEXA FLUOR® 594
Purified by Protein A.
Human, Mouse, Rat
ALEXA FLUOR® 594
Alexa conjugate 1
1ug per 1ul