anti-p53 (Ab 18) Antibody

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Product price

180 EUR

Product size

0.1 mg

Product catalog no.

79-531

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Gene info

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

 

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Suspention, pH, azide

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

 

Antigen

p53 (Ab-18) antibody was made against a peptide sequence around aa. 16~20 (Q-E-T-F-S) derived from Human p53.

Gene names

P53, BCC7, LFS1, TRP53, MTC, TRK, TRKA, Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13

 

Purity

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Spicific to

This antibody detects endogenous level of total p53 protein.

 

Keep at

Store antibody at -20 grades C for up to one year.

Antibody advice

Western Blot: 1:500~1:1000

 

Antigene name

tumor protein p53

Antibodie's label

unlabelled serum

 

Source

Homo sapiens

Immuno application

Western Blot

 

Ncbi nr

NP_000537.3

Vial with antibody

in solution

 

Type

Polyclonal

Omim nr

120407068

 

French translation

anticorps

Quantity per ml

1 mg/mL

 

KDa

53 kDa

Protein nr

P04637

 

Ab raised in

Rabbit

Works with

Human

 

NCBI GENE nr

7157

GENE symbol

TP53