anti-p53 (phospho Ser33) Antibody

The best quality, top anti-p53 (phospho Ser33) Antibody prices, fast delivery.

Product price

180 EUR

Product size

0.1 mg

Product catalog no.

79-447

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Gene info

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.

Purity

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

 

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Antigen

p53 (Phospho-Ser33) antibody was made against a peptide sequence around phosphorylation site of serine 33 (V-L-S (p) -P-L) derived from Human p53.

 

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Suspention, pH, azide

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

 

Gene names

P53, BCC7, LFS1, TRP53, HSP27, HSP28, Antigen NY-CO-13, Phosphoprotein p53, TP53, Tumor suppressor p53

Spicific to

This antibody detects endogenous level of p53 only when phosphorylated at serine 33.

 

Antibody advice

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Keep at

Store antibody at -20 grades C for up to one year.

 

Immuno application

Western Blot, immuno fluorescence

Antigene name

tumor protein p53

 

Antibodie's label

unlabelled serum

Source

Homo sapiens

 

Ncbi nr

NP_000537.3

Vial with antibody

in solution

 

Type

Polyclonal

Omim nr

120407068

 

French translation

anticorps

Quantity per ml

1 mg/mL

 

KDa

53 kDa

Protein nr

P04637

 

Ab raised in

Rabbit

Works with

Human

 

NCBI GENE nr

7157

GENE symbol

TP53