The best quality, top anti-TP53BP1 Antibody prices, fast delivery.
180 EUR
0.025 mL
48-864
P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability. Tumor protein p53 binding protein 1 binds to the central domain of p53 required for site-specific DNA binding thus inhibiting the ability of p53 to bind DNA. TP53BP1 also functions as a checkpoint protein with properties of a DNA double-strand break sensor. It is a putative substrate of ATM kinase and is phosphorylated in response to DNA damage and localizes to sites of double-strand breaks.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
TP53BP1 antibody was made against a synthetic peptide corresponding to the carboxy - terminus of TP53BP1 (Human).
Aliquot and store TP53BP1 antibody at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
TP53BP1 antibody can be used in ELISA, and immunohistochemistry starting at 5 ug/mL.
TP53BP1, 53BP1, p202, p53-binding protein 1, p53-binding protein 53bp1, p53BP1
Western Blot, immuno-histo-chemistry
PBS, pH 7.2, no preservatives added.
tumor protein p53 binding protein 1
Affinity Chromatography
unlabelled serum
Homo sapiens
in solution
Polyclonal
anticorps
TP53BP1
8928568
Q12888
Q12888
Rabbit
Human
7158
IgG