anti-p53R2 Antibody

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Product price

180 EUR

Product size

0.02 mg, 0.1 mg

Product catalog no.

2383

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Gene info

p53R2 Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.

Keep at

p53R2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

 

Antibody advice

p53R2 antibody can be used for detection of p53R2 by Western blot at 0.5 to 1 ug/mL. A 39 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 1 ug/mL. For immunofluorescence start at 20 ug/mL.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

 

Gene names

p53R2 Antibody: P53R2, MTDPS8A, MTDPS8B, P53R2, Ribonucleoside-diphosphate reductase subunit M2 B, TP53-inducible ribonucleotide reductase M2 B, p53R2

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Antigen

p53R2 antibody was made against a 16 amino acid peptide near the amino terminus of human p53R2.

Purity

p53R2 Antibody is affinity chromatography purified via peptide column.

 

Immuno application

ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence

Suspention, pH, azide

p53R2 Antibody is supplied in PBS containing 0.02% sodium azide.

 

Antigene name

ribonucleotide reductase M2 B (TP53 inducible)

Works with

Human, Mouse, Rat

 

Antibodie's label

unlabelled serum

Source

Homo sapiens

 

Vial with antibody

in solution

Type

Polyclonal

 

French translation

anticorps

Ncbi nr

BAA92434

 

Omim nr

7229086

KDa

39 kDa

 

Protein nr

Q7LG56

Ab raised in

Rabbit

 

NCBI GENE nr

50484

GENE symbol

RRM2B

 

Immunoglobulin

IgG